Description

2-(2-Chloro-Acetylamino)-4-(3,4-Dimethoxy-Phenyl)-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring a thiophene core with chloroacetamide and dimethoxyphenyl substituents, makes it a versatile precursor for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Acts as a building block for organic semiconductors, conductive polymers, and advanced materials due to its electron-rich thiophene and aromatic systems.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-(2-Chloro-Acetylamino)-4-(3,4-Dimethoxy-Phenyl)-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	304863-82-9
Molecular Formula	C17H18ClNO5S
Molecular Weight	383.85 g/mol
Synonyms	Ethyl 2-[(2-chloroacetyl)amino]-4-(3,4-dimethoxyphenyl)thiophene-3-carboxylate; 2-[(2-Chloroacetyl)amino]-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylic Acid Ethyl Ester; 4-(3,4-Dimethoxyphenyl)-2-[(2-chloroacetyl)amino]thiophene-3-carboxylic Acid Ethyl Ester; Thiophene-3-carboxylic acid, 2-[(2-chloroacetyl)amino]-4-(3,4-dimethoxyphenyl)-, ethyl ester; CAS 304863-82-9
EINECS	Contact for details

Quality Control

Our production of 2-(2-Chloro-Acetylamino)-4-(3,4-Dimethoxy-Phenyl)-Thiophene-3-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to support regulatory filings in pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.