Description

2-Chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thien-2-yl)acetamide is a high-value, heterocyclic organic building block featuring a fused cyclopentathiophene core. This compound matters for its role as a critical synthetic intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, or insecticides, leveraging its unique heterocyclic structure for bioactivity.
• Material Science: Potential building block for organic electronic materials, such as organic semiconductors or non-linear optical (NLO) materials, due to the electron-rich thiophene moiety.
• Chemical Biology: Employed as a scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers engaged in custom synthesis and scale-up projects.

Basic Information

Product Name	2-Chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thien-2-yl)acetamide
CAS No.	304685-87-8
Molecular Formula	C10H9ClN2OS
Molecular Weight	240.71 g/mol
Synonyms	2-Chloro-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)acetamide; 2-Chloroacetamide, N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thien-2-yl)-; Acetamide, 2-chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thien-2-yl)-; 2-Chloro-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)acetamide; 304685-87-8; N-(3-Cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-2-chloroacetamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thien-2-yl)acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.