Description

2-Amino-4-Phenyl-5-Thiocyanato-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both amino and thiocyanato functional groups on a thiophene core, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and insecticides, leveraging the thiophene scaffold's bioactivity.
• Material Science Precursor: Acts as a monomer or building block for the synthesis of conjugated polymers and organic semiconductors with potential applications in OLEDs and organic photovoltaics.
• Dye and Pigment Synthesis: Employed in the creation of specialized heterocyclic dyes and colorants due to its electron-rich structure.
• Ligand Synthesis for Catalysis: Utilized to prepare novel nitrogen- and sulfur-containing ligands for transition metal catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and CROs.

Basic Information

Product Name	2-Amino-4-Phenyl-5-Thiocyanato-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	304646-76-2
Molecular Formula	C14H12N2O2S2
Molecular Weight	304.39 g/mol
Synonyms	Ethyl 2-Amino-4-phenyl-5-thiocyanatothiophene-3-carboxylate; 2-Amino-4-phenyl-5-thiocyanatothiophene-3-carboxylic acid ethyl ester; 5-Thiocyanato-2-amino-4-phenylthiophene-3-carboxylic acid ethyl ester; ATCTE; 304646-76-2; Thiophene-3-carboxylic acid, 2-amino-4-phenyl-5-thiocyanato-, ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Phenyl-5-Thiocyanato-Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.