Description

Methyl 3-Amino-5-(3-Chlorophenyl)Thiophene-2-Carboxylate is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in the development of advanced pharmaceutical and agrochemical active ingredients. It is primarily sought by research and development chemists, process development teams, and manufacturers in the life sciences sector for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and advanced organic electronic materials due to its thiophene core.
• Chemical Biology & Proteomics: Employed as a building block for creating specialized molecular probes, enzyme inhibitors, and tagged compounds for biological studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	Methyl 3-Amino-5-(3-Chlorophenyl)Thiophene-2-Carboxylate
CAS No.	304477-85-8
Molecular Formula	C12H10ClNO2S
Molecular Weight	267.73 g/mol
Synonyms	Methyl 3-amino-5-(3-chlorophenyl)thiophene-2-carboxylate; 3-Amino-5-(3-chlorophenyl)thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-5-(3-chlorophenyl)-, methyl ester; Methyl 3-amino-5-(m-chlorophenyl)thiophene-2-carboxylate; 304477-85-8; 3-Amino-5-(3-chlorophenyl)-2-thiophenecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-5-(3-Chlorophenyl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.