Description

(2-Amino-4,5,6,7-Tetrahydro-1-Benzothien-3-Yl)(4-Fluorophenyl)Methanone CAS NO 304018-11-9 is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzothiophene core structure. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and R&D organizations focused on developing new therapeutic agents, particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Integral in the multi-step synthesis of complex, high-value APIs, particularly those containing fused heterocyclic systems.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory synthetic chemistry and pharmacological studies.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for custom synthesis projects and scale-up activities.

Basic Information

Product Name	(2-Amino-4,5,6,7-Tetrahydro-1-Benzothien-3-Yl)(4-Fluorophenyl)Methanone
CAS No.	304018-11-9
Molecular Formula	C15H14FNOS
Molecular Weight	275.34 g/mol
Synonyms	2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonyl-4'-fluorobenzene; 4-Fluorophenyl(2-amino-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)methanone; (2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)(4-fluorophenyl)methanone; 304018-11-9; 4-Fluoro-(2-amino-4,5,6,7-tetrahydrobenzo[b]thien-3-yl)phenylmethanone; Methanone, (2-amino-4,5,6,7-tetrahydro-1-benzothien-3-yl)(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our (2-Amino-4,5,6,7-Tetrahydro-1-Benzothien-3-Yl)(4-Fluorophenyl)Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.