Description

(2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophen-3-Yl)-(4-Chloro-Phenyl)-Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused-ring thiophene structure. This compound is a critical building block in modern organic synthesis, valued for its role in constructing complex molecular architectures with potential biological activity. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric conditions.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex heterocyclic compounds due to its reactive amino and ketone functional groups.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs within drug discovery pipelines.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents, leveraging its heterocyclic core.

Basic Information

Product Name	(2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophen-3-Yl)-(4-Chloro-Phenyl)-Methanone
CAS No.	304018-04-0
Molecular Formula	C14H12ClNOS
Molecular Weight	277.77 g/mol
Synonyms	2-Amino-4,5,6,7-tetrahydro-3-(4-chlorobenzoyl)thieno[2,3-c]pyridine; (2-Amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-3-yl)(4-chlorophenyl)methanone; 4-Chloro-phenyl-(2-amino-4,5,6,7-tetrahydro-thieno[2,3-c]pyridin-3-yl)-methanone; 304018-04-0; 4-Chlorophenyl(2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-3-yl)methanone
EINECS	Contact for details

Quality Control

Our (2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophen-3-Yl)-(4-Chloro-Phenyl)-Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.