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Methyl 3-(1-[2-(1H-Pyrrol-1-Yl)[1,2,4]Triazolo[1,5-A]Pyrimidin-7-Yl]Ethoxy)-2-Thiophenecarboxylate CAS NO 303146-16-9


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CAS No.:303146-16-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 3-(1-[2-(1H-Pyrrol-1-Yl)[1,2,4]Triazolo[1,5-A]Pyrimidin-7-Yl]Ethoxy)-2-Thiophenecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly in oncology and antiviral research.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel triazolopyrimidine-based drug candidates.
  • Oncology Research: Used in the development of targeted cancer therapies and kinase inhibitors.
  • Antiviral Drug Development: Employed in research programs focused on creating new antiviral agents.
  • Agrochemical Research: Potential application in the synthesis of new-generation pesticides and herbicides.
  • Material Science: Investigated for use in the creation of specialty polymers and organic electronic materials.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name Methyl 3-(1-[2-(1H-Pyrrol-1-Yl)[1,2,4]Triazolo[1,5-A]Pyrimidin-7-Yl]Ethoxy)-2-Thiophenecarboxylate
CAS No. 303146-16-9
Molecular Formula C17H15N5O3S
Molecular Weight 369.40 g/mol
Synonyms Methyl 3-[(1-{2-[(1H-pyrrol-1-yl)][1,2,4]triazolo[1,5-a]pyrimidin-7-yl}ethoxy)-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 3-[1-[2-(1H-pyrrol-1-yl)[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]ethoxy]-, methyl ester; CAS 303146-16-9; 7-(1-Hydroxyethyl)-2-(1H-pyrrol-1-yl)[1,2,4]triazolo[1,5-a]pyrimidine-3-carboxylic acid methyl ester derivative (related structure).
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Quality Control

Our production of Methyl 3-(1-[2-(1H-Pyrrol-1-Yl)[1,2,4]Triazolo[1,5-A]Pyrimidin-7-Yl]Ethoxy)-2-Thiophenecarboxylate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and development grade specifications. Certificates of Analysis (COA) detailing all test results are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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