Description

Dimethyl 5-(4-Methylphenyl)-2,3-Dihydro-1H-Pyrrolizine-6,7-Dicarboxylate is a high-purity, synthetic pyrrolizine derivative serving as a critical advanced intermediate in modern organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. Pharmaceutical research organizations, agrochemical innovators, and specialty chemical manufacturers need this precise chemical building block to drive their R&D and process development efforts forward.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic cores.
• Agrochemical Synthesis: Used in the synthesis of advanced crop protection agents and herbicides, leveraging its unique pyrrolizine scaffold for biological activity.
• Material Science Research: Serves as a precursor for organic electronic materials, including charge-transport layers or light-emitting components in OLED research.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Academic & Industrial R&D: A versatile building block for methodological chemistry research, including catalysis studies and the development of new synthetic methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, low-volume specialty chemicals for niche industrial applications.

Basic Information

Product Name	Dimethyl 5-(4-Methylphenyl)-2,3-Dihydro-1H-Pyrrolizine-6,7-Dicarboxylate
CAS No.	303145-34-8
Molecular Formula	C19H21NO4
Molecular Weight	327.38 g/mol
Synonyms	Dimethyl 5-(p-Tolyl)-2,3-dihydro-1H-pyrrolizine-6,7-dicarboxylate; 6,7-Dimethoxycarbonyl-5-(4-methylphenyl)-2,3-dihydro-1H-pyrrolizine; 5-(4-Methylphenyl)-2,3-dihydro-1H-pyrrolizine-6,7-dicarboxylic Acid Dimethyl Ester; 1H-Pyrrolizine-6,7-dicarboxylic acid, 2,3-dihydro-5-(4-methylphenyl)-, dimethyl ester; Dimethyl 5-(4-Methylphenyl)-2,3-dihydropyrrolizine-6,7-dicarboxylate
EINECS	Contact for details

Quality Control

Our Dimethyl 5-(4-Methylphenyl)-2,3-Dihydro-1H-Pyrrolizine-6,7-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.