Description

6,7-Dimethoxy-1,2,3,4-Tetrahydro-1-Isoquinoline Acetic Acid Monohydrate, 99 is a high-purity, advanced pharmaceutical intermediate characterized by its monohydrate crystalline form. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing complex bioactive molecules. It is primarily sought by pharmaceutical companies, contract research organizations (CROs), and academic laboratories engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex alkaloids and other active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular systems.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and the development of novel drug candidates.
• Biochemical Research: Employed in studies investigating enzyme inhibition and receptor-ligand interactions due to its specific isoquinoline structure.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Chemical Synthesis: Utilized in organic synthesis for constructing complex heterocyclic compounds with potential biological activity.

Basic Information

Product Name	6,7-Dimethoxy-1,2,3,4-Tetrahydro-1-Isoquinoline Acetic Acid Monohydrate, 99
CAS No.	303094-23-7
Molecular Formula	C₁₃H₁₇NO₅ • H₂O
Molecular Weight	283.28 g/mol (Monohydrate)
Synonyms	1,2,3,4-Tetrahydro-6,7-dimethoxy-1-isoquinolineacetic acid monohydrate; 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-acetic acid hydrate; (6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-1-yl)acetic acid monohydrate; TDQAA; THIQ Acetic Acid Derivative; NSC 760463 (monohydrate); 1-Carboxymethyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline monohydrate
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-1,2,3,4-Tetrahydro-1-Isoquinoline Acetic Acid Monohydrate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets the specified 99% minimum purity and is free from critical impurities. A detailed Certificate of Analysis (COA) providing results for identity, purity, residual solvents, and related substances is supplied with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0%
Water Content (KF)	5.0% - 7.5% (Theoretical for monohydrate: ~6.36%)
Related Substances (HPLC)	Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.