Description

4-Bromo-3-Formylindole-1-Carboxylic Acid tert-Butyl Ester is a high-value, multi-functional indole derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both bromo and formyl substituents on the indole core, makes it an indispensable precursor for constructing complex heterocyclic systems and pharmaceutical intermediates. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potent kinase inhibitors, receptor antagonists, and other biologically active indole-based molecules.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Used in the research and development of organic semiconductors, light-emitting diodes (OLEDs), and advanced polymeric materials.
• Chemical Biology: Serves as a versatile probe or linker in the design of activity-based protein profiling (ABPP) agents and other biochemical tools.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry, including cross-coupling reactions and palladium-catalyzed transformations.

Basic Information

Product Name	4-Bromo-3-Formylindole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	303041-88-5
Molecular Formula	C14H14BrNO3
Molecular Weight	324.17 g/mol
Synonyms	1-Boc-4-bromo-3-formylindole; tert-Butyl 4-bromo-3-formyl-1H-indole-1-carboxylate; 4-Bromo-3-formyl-1H-indole-1-carboxylic acid tert-butyl ester; 1H-Indole-1-carboxylic acid, 4-bromo-3-formyl-, 1,1-dimethylethyl ester; 4-Bromoindole-3-carboxaldehyde-1-Boc; 1-Boc-4-bromoindole-3-carboxaldehyde; BOC-4-Bromo-3-formylindole
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Formylindole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing results from HPLC, NMR, and other relevant analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.