Description

Ethyl 2-(tert-Butoxycarbonylamino)Thiazole-5-Carboxylate is a high-purity, protected amino acid derivative and a key synthetic intermediate in modern organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for peptide-mimetic synthesis and heterocyclic chemistry applications.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of drug candidates, particularly those containing thiazole and peptide-like structures.
• Peptidomimetic Research: Used in medicinal chemistry to create stable, bioavailable analogs of natural peptides for therapeutic development.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced pesticides and herbicides with specific biological activity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science: A potential monomer or modifier in the creation of specialized polymers with unique electronic or structural properties.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up development.

Basic Information

Product Name	Ethyl 2-(tert-Butoxycarbonylamino)Thiazole-5-Carboxylate
CAS No.	302964-01-8
Molecular Formula	C11H16N2O4S
Molecular Weight	272.32 g/mol
Synonyms	5-Thiazolecarboxylic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, ethyl ester; Ethyl 2-[(tert-Butoxycarbonyl)amino]-1,3-thiazole-5-carboxylate; 2-(Boc-amino)thiazole-5-carboxylic acid ethyl ester; Boc-Thz(5-COOEt)-OH; Ethyl 2-(Boc-amino)-5-thiazolecarboxylate; t-Butyl N-(5-ethoxycarbonyl-2-thiazolyl)carbamate; 302964-01-8; Boc-Thz(COOEt)-OH
EINECS	Contact for details

Quality Control

Our Ethyl 2-(tert-Butoxycarbonylamino)Thiazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support research and cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.