Description

n-Boc-Amino-4-Methylthiazole-5-Carboxylic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceuticals and bioactive molecules, offering a versatile handle for peptide coupling and further functionalization. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and antiviral research.
• Peptidomimetic Synthesis: Used to incorporate the 4-methylthiazole-5-carboxylic acid moiety into peptide backbones to enhance metabolic stability and binding affinity.
• Combinatorial Chemistry: Employed in solid-phase and solution-phase parallel synthesis for the rapid generation of compound libraries for high-throughput screening.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and herbicides.
• Bioconjugation: Utilized in the design of chemical probes, linkers, and antibody-drug conjugates (ADCs) due to its reactive carboxylic acid group.
• Material Science: Investigated for the creation of novel polymers and functional materials with specific electronic or biological properties.

Basic Information

Product Name	n-Boc-Amino-4-Methylthiazole-5-Carboxylic Acid
CAS No.	302963-94-6
Molecular Formula	C10H14N2O4S
Molecular Weight	258.29 g/mol
Synonyms	5-[(tert-Butoxycarbonyl)amino]-4-methyl-1,3-thiazole-2-carboxylic Acid; 2-[(tert-Butoxycarbonyl)amino]-4-methyl-1,3-thiazole-5-carboxylic Acid; Boc-AMTCA; tert-Butyl (5-carboxy-4-methylthiazol-2-yl)carbamate; N-Boc-2-amino-4-methylthiazole-5-carboxylic acid; 4-Methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-thiazole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our n-Boc-Amino-4-Methylthiazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.