Description

m-Cresol-D8 is a deuterated isotopologue of meta-cresol, where eight hydrogen atoms are replaced with deuterium, a stable hydrogen isotope. This high isotopic purity makes it an essential internal standard and tracer in advanced analytical chemistry, particularly for quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. It is critically needed by researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental science sectors for precise method development and accurate quantification of its non-deuterated counterpart.

Application

• Used as a stable isotope-labeled internal standard for the accurate quantification of m-cresol in complex biological and environmental matrices via GC-MS or LC-MS.
• Serves as a crucial tracer molecule in metabolic pathway studies and pharmacokinetic research within pharmaceutical development.
• Employed in NMR spectroscopy as a deuterated solvent or shift reference to simplify spectral analysis and avoid signal interference.
• Applied in material science research to study reaction mechanisms and polymer dynamics where hydrogen/deuterium exchange is relevant.
• Facilitates quality control and method validation in industrial settings for the production of cresol-based chemicals, resins, and disinfectants.
• Essential for environmental analysis, tracing the fate and degradation of phenolic compounds in ecological studies.

Basic Information

Product Name	m-Cresol-D8
CAS No.	302911-90-6
Molecular Formula	C7D8O
Molecular Weight	116.21 g/mol
Synonyms	3-Methylphenol-D8; Deuterated m-Cresol; 3-(Trideuteriomethyl)(2H5)phenol; meta-Cresol-d8; 3-Hydroxytoluene-D8; Perdeuterated m-Cresol; (2,3,4,5,6-D5)-3-(Methyl-D3)phenol
EINECS	Contact for details

Quality Control

Our m-Cresol-D8 is manufactured under controlled conditions to ensure high chemical and isotopic purity, meeting the stringent requirements for analytical reference standards. Each batch undergoes rigorous testing, including analysis by NMR and mass spectrometry to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥98 atom % D), chemical purity, and specific analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider sealing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Isotopic Purity (Atom % D)	≥ 98%
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.