Description

5-[(1-Benzyl-1H-Indol-3-Yl)Methylene]-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione is a sophisticated heterocyclic organic compound that serves as a critical building block and intermediate in advanced chemical synthesis. Its unique molecular architecture, featuring fused indole and pyrimidine-dione rings, makes it a valuable scaffold for research and development in medicinal chemistry. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways or receptor sites.
• Medicinal Chemistry Research: Used as a core scaffold for constructing combinatorial libraries to screen for new biological activity in drug discovery programs.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the benzyl-indole-thioxodihydropyrimidinedione moiety into larger, more complex molecules.
• Biochemical Probe Development: Utilized in academic and industrial research to create molecular probes for studying biological processes and protein interactions.
• Fine Chemical Production: Serves as an intermediate in the manufacture of specialty chemicals used in agrochemicals or advanced material science.

Basic Information

Product Name	5-[(1-Benzyl-1H-Indol-3-Yl)Methylene]-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione
CAS No.	302824-19-7
Molecular Formula	C20H15N3O2S
Molecular Weight	361.42 g/mol
Synonyms	5-[(1-Benzyl-1H-indol-3-yl)methylene]-2-thioxo-1,2,3,4-tetrahydropyrimidine-4,6-dione; 1-Benzyl-3-[(4,6-dioxo-2-thioxo-1,2,3,4,5,6-hexahydropyrimidin-5-ylidene)methyl]-1H-indole; 2-Thioxo-5-[(1-benzyl-1H-indol-3-yl)methylene]dihydropyrimidine-4,6(1H,5H)-dione; 5-(1-Benzylindol-3-ylmethylene)-2-thiobarbituric acid; 5-(1-Benzyl-1H-indol-3-ylmethylene)pyrimidine-2,4,6(1H,3H,5H)-trithione (tautomeric form); BTIP Derivative
EINECS	Contact for details

Quality Control

Every batch of 5-[(1-Benzyl-1H-Indol-3-Yl)Methylene]-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione is manufactured and tested under a strict quality management system. We ensure compliance with relevant standards for research-grade chemicals. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. Certificates of Analysis (COA) detailing all test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.