Description

Ethyl 5-Methyl-3-(2,2,2-Trifluoroacetylamino)-2,4-Thiazolecarboxylate is a high-value, multifunctional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a unique trifluoroacetyl-protected amino group on a thiazole core. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of antiviral, antibacterial, and anti-inflammatory agents.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, including fungicides and herbicides, leveraging the stability of the thiazole ring.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential building block for the synthesis of specialty polymers, ligands, or functional materials requiring specific heterocyclic architectures.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring precise, high-purity fluorinated heterocycles.

Basic Information

Product Name	Ethyl 5-Methyl-3-(2,2,2-Trifluoroacetylamino)-2,4-Thiazolecarboxylate
CAS No.	302804-92-8
Molecular Formula	C9H9F3N2O3S
Molecular Weight	282.24 g/mol
Synonyms	Ethyl 5-methyl-3-[(2,2,2-trifluoroacetyl)amino]-1,3-thiazole-4-carboxylate; 2,4-Thiazolecarboxylic acid, 5-methyl-3-[(2,2,2-trifluoroacetyl)amino]-, ethyl ester; 3-(2,2,2-Trifluoroacetamido)-5-methylthiazole-4-carboxylic acid ethyl ester; 5-Methyl-3-(trifluoroacetylamino)thiazole-4-carboxylic acid ethyl ester; Ethyl 5-methyl-3-(trifluoroacetylamino)thiazole-4-carboxylate; 302804-92-8; TFAT ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 5-Methyl-3-(2,2,2-Trifluoroacetylamino)-2,4-Thiazolecarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the rigorous standards required for pharmaceutical and agrochemical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.