Description

Dimethyl 2-[([1,1'-Biphenyl]-4-Ylcarbonyl)Amino]-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3,4-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and proprietary drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry for creating libraries of compounds for biological screening and lead optimization.
• Chemical Synthesis Research: Serves as a versatile precursor for constructing complex fused-ring systems containing thiophene and cyclopentane motifs.
• Material Science Research: Potential precursor for specialty organic electronic materials due to its conjugated biphenyl and heterocyclic structure.
• Contract Research Organizations (CROs): Supplied to CROs supporting pharmaceutical and biotech companies in preclinical development.

Basic Information

Product Name	Dimethyl 2-[([1,1'-Biphenyl]-4-Ylcarbonyl)Amino]-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3,4-Dicarboxylate
CAS No.	302802-60-4
Molecular Formula	C30H25NO5S
Molecular Weight	511.59 g/mol
Synonyms	Dimethyl 2-[(4-phenylbenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3,4-dicarboxylate; 2-[(4-Biphenylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3,4-dicarboxylic acid dimethyl ester; 4,5,6,7-Tetrahydro-2-[[(1,1'-biphenyl)-4-ylcarbonyl]amino]-1-benzothiophene-3,4-dicarboxylic acid dimethyl ester; Biphenyl-4-carboxylic acid [3,4-bis(methoxycarbonyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]amide
EINECS	Contact for details

Quality Control

Our Dimethyl 2-[([1,1'-Biphenyl]-4-Ylcarbonyl)Amino]-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.