Description

2-Amino-n-Methyl-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex heterocyclic compounds containing thiophene and cycloheptane motifs.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of proprietary compounds under cGMP conditions.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	2-Amino-n-Methyl-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxamide
CAS No.	301321-97-1
Molecular Formula	C11H16N2OS
Molecular Weight	224.32 g/mol
Synonyms	2-Amino-N-methyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide; 2-Amino-N-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide (related bicyclic name); AMTCC; Cycloheptathiophene carboxamide derivative; CAS 301321-97-1
EINECS	Contact for details

Quality Control

Our 2-Amino-n-Methyl-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, impurities, and other critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.