Description

6-[(5Z)-5-(1-Acetyl-2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)-4-Oxo-2-Thioxo-1,3-Thiazolidin-3-Yl]Hexanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Biochemical Probe Development: Serves as a core scaffold for creating tools to study enzyme inhibition or protein-ligand interactions.
• Organic Synthesis Building Block: Employed in complex organic transformations to construct fused indole-thiazolidinone systems.
• High-Value Fine Chemical Production: Supplied for the cGMP or non-GMP manufacture of active pharmaceutical ingredients (APIs) in clinical trial stages.

Basic Information

Product Name	6-[(5Z)-5-(1-Acetyl-2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)-4-Oxo-2-Thioxo-1,3-Thiazolidin-3-Yl]Hexanoic Acid
CAS No.	300816-71-1
Molecular Formula	C21H20N2O5S2
Molecular Weight	444.52 g/mol
Synonyms	6-[(5Z)-5-(1-Acetyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]hexanoic acid; 3-[6-(1-Acetyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]hexanoic acid; (5Z)-5-(1-Acetyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-3-(5-carboxypentyl)-2-thioxo-1,3-thiazolidin-4-one; 300816-71-1; Indole-thiazolidinone derivative; Hexanoic acid, 6-[(5Z)-5-(1-acetyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-
EINECS	Contact for details

Quality Control

Our 6-[(5Z)-5-(1-Acetyl-2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)-4-Oxo-2-Thioxo-1,3-Thiazolidin-3-Yl]Hexanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere when appropriate for long-term storage or after opening. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.