Description

1,3,4,5-Tetrahydro-Pyrido[4,3-B]Indole-2,8-Dicarboxylic Acid 2-tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic indole structure. This compound is critical for the synthesis of sophisticated active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and scale-up of novel drug candidates.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the production of complex drug molecules, particularly in neurological and psychiatric research.
• Research & Development (R&D): Used in medicinal chemistry for lead optimization and the discovery of new chemical entities with potential biological activity.
• Process Chemistry & Scale-Up: Employed in pilot plants and commercial manufacturing for the development of robust and efficient synthetic routes to target APIs.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs producing custom APIs and advanced intermediates for global pharmaceutical clients.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method validation in API production.

Basic Information

Product Name	1,3,4,5-Tetrahydro-Pyrido[4,3-B]Indole-2,8-Dicarboxylic Acid 2-tert-Butyl Ester
CAS No.	300715-96-2
Molecular Formula	C18H20N2O4
Molecular Weight	328.36 g/mol
Synonyms	2-tert-Butyl 1,3,4,5-tetrahydropyrido[4,3-b]indole-2,8-dicarboxylate; 2-(tert-Butoxycarbonyl)-1,3,4,5-tetrahydropyrido[4,3-b]indole-8-carboxylic Acid; 8-Carboxy-2-Boc-1,3,4,5-tetrahydropyrido[4,3-b]indole; 2-Boc-8-COOH-1,3,4,5-tetrahydropyrido[4,3-b]indole; Pyrido[4,3-b]indole-2,8-dicarboxylic acid, 1,3,4,5-tetrahydro-, 2-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our 1,3,4,5-Tetrahydro-Pyrido[4,3-B]Indole-2,8-Dicarboxylic Acid 2-tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.