Description

2-(2-Chloro-Acetylamino)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily required by R&D laboratories and manufacturing facilities in the pharmaceutical and fine chemical industries for the development and production of new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those containing the cyclopentathiophene scaffold.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• API Synthesis: Serves as a building block in multi-step synthetic routes for the production of target Active Pharmaceutical Ingredients.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals for advanced material science applications.

Basic Information

Product Name	2-(2-Chloro-Acetylamino)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	300676-39-5
Molecular Formula	C12H12ClNO3S
Molecular Weight	285.75 g/mol
Synonyms	Methyl 2-(2-chloroacetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate; 2-(2-Chloroacetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid methyl ester; 2-(2-Chloroacetylamino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic Acid Methyl Ester; 300676-39-5; Cyclopenta[b]thiophene-3-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-Acetylamino)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.