Description

4-Ethyl 2-Methyl 5-[(Chloroacetyl)Amino]-3-Methylthiophene-2,4-Dicarboxylate is a high-purity, multi-functional thiophene derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in its unique molecular architecture, which provides a versatile scaffold for constructing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides, herbicides, and fungicides, leveraging the bioactivity of the thiophene core.
• Material Science Research: Serves as a precursor for functional organic materials, including organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions due to its modifiable functional groups.
• Custom Synthesis & Contract Manufacturing: An important starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	4-Ethyl 2-Methyl 5-[(Chloroacetyl)Amino]-3-Methylthiophene-2,4-Dicarboxylate
CAS No.	300676-14-6
Molecular Formula	C14H16ClNO5S
Molecular Weight	345.80 g/mol
Synonyms	5-[(Chloroacetyl)amino]-3-methyl-4-ethyl-2-methylthiophene-2,4-dicarboxylate; 3-Methyl-5-[(chloroacetyl)amino]-4-ethyl-2-methylthiophene-2,4-dicarboxylic acid ester; Methyl 5-[(chloroacetyl)amino]-3-methyl-4-ethylthiophene-2,4-dicarboxylate; Thiophene-2,4-dicarboxylic acid, 5-[(chloroacetyl)amino]-3-methyl-4-ethyl-, dimethyl ester; CAS 300676-14-6
EINECS	Contact for details

Quality Control

Our production of 4-Ethyl 2-Methyl 5-[(Chloroacetyl)Amino]-3-Methylthiophene-2,4-Dicarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.