Description

Diethyl [(2-Pyridinyl)Methyl]Phosphonate is a versatile organophosphorus compound featuring a pyridinylmethyl group, making it a valuable synthetic intermediate and ligand precursor. This chemical is critical for facilitating carbon-carbon and carbon-heteroatom bond formation in complex molecule synthesis, offering researchers and manufacturers a reliable building block. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of drug candidates, particularly those containing pyridine and phosphonate moieties for therapeutic applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators requiring specific phosphonate esters.
• Ligand Precursor: Serves as a starting material for the preparation of specialized phosphine ligands used in catalysis and metal complexation.
• Organic Synthesis Reagent: Employed in Horner-Wadsworth-Emmons (HWE) and related olefination reactions to construct alkenes with high stereoselectivity.
• Material Science Research: Utilized in the development of novel polymers, flame retardants, and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Acts as a scaffold for creating enzyme inhibitors or molecular probes targeting biological phosphate-binding sites.

Basic Information

Product Name	Diethyl [(2-Pyridinyl)Methyl]Phosphonate
CAS No.	39996-87-7
Molecular Formula	C10H16NO3P
Molecular Weight	229.21 g/mol
Synonyms	Diethyl (2-Pyridylmethyl)phosphonate; (2-Pyridinylmethyl)phosphonic Acid Diethyl Ester; Diethyl (Pyridin-2-ylmethyl)phosphonate; Phosphonic Acid, P-[(2-Pyridinyl)methyl]-, Diethyl Ester; Diethyl 2-Pyridylmethylphosphonate; Diethyl (2-Pyridylmethyl)phosphonate; (Pyridin-2-ylmethyl)phosphonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl [(2-Pyridinyl)Methyl]Phosphonate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications and test results is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.