Description

p-Hydroxy-5,6-Dehydrokawain is a bioactive kavalactone derivative, a key compound of interest in advanced phytochemical research and development. This compound matters for its role as a reference standard and a potential active pharmaceutical ingredient (API) intermediate, offering high purity for precise analytical and formulation work. It is needed by research institutions, pharmaceutical developers, and nutraceutical manufacturers focused on natural product chemistry and therapeutic innovation.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of kavalactone-containing products in HPLC, LC-MS, and other chromatographic methods.
• Natural Product Research: Serves as a critical biochemical tool for studying the pharmacological properties, metabolism, and structure-activity relationships of kavalactones.
• Nutraceutical Development: Employed as a high-purity ingredient in the formulation of standardized botanical extracts and dietary supplements.
• API Intermediate Synthesis: Acts as a key building block in the synthetic pathways for developing novel therapeutic agents.
• Quality Control Laboratories: Essential for method development, validation, and ensuring batch-to-batch consistency in industries handling kava or related botanicals.

Basic Information

Product Name	p-Hydroxy-5,6-Dehydrokawain
CAS No.	39986-86-2
Molecular Formula	C₁₄H₁₂O₄
Molecular Weight	244.24 g/mol
Synonyms	5,6-Dehydro-7,8-dihydrokawain-4-ol; 4-Hydroxy-5,6-dehydrokavain; 7,8-Dihydro-5,6-dehydrokawain-4-ol; (E)-4-Hydroxy-6-styryl-2-pyrone; 4-Hydroxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one; 4-Hydroxy-6-styryl-2-pyrone; A key kavalactone derivative.
EINECS	Contact for details

Quality Control

Our p-Hydroxy-5,6-Dehydrokawain is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.