Description

Methyl 3-Aminothiophene-4-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant heterocyclic building block primarily used in the synthesis of active pharmaceutical ingredients (APIs). This compound is valued for its role as a versatile intermediate in medicinal chemistry, enabling the construction of complex molecules with potential biological activity. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the thiophene scaffold for bioactive molecule design.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials and conductive polymers.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks and exploring new chemical reactions.
• Bioconjugation & Probe Development: The amine and ester functional groups make it suitable for creating fluorescent probes or bioconjugates for diagnostic applications.

Basic Information

Product Name	Methyl 3-Aminothiophene-4-Carboxylate Hydrochloride
CAS No.	39978-14-8
Molecular Formula	C6H8ClNO2S
Molecular Weight	193.65 g/mol
Synonyms	3-Amino-4-(methoxycarbonyl)thiophene hydrochloride; Methyl 3-amino-4-thiophenecarboxylate hydrochloride; 3-Amino-4-carbomethoxythiophene hydrochloride; 4-(Methoxycarbonyl)thiophen-3-amine hydrochloride; 3-Aminothiophene-4-carboxylic acid methyl ester hydrochloride; Thiophene-3-amine, 4-(methoxycarbonyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 3-Aminothiophene-4-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.