Description

1-Bromo-4-Cyclobutyl-Benzene is a versatile halogenated aromatic building block featuring a cyclobutyl substituent. This compound matters for its role as a key intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those requiring a cyclobutyl-aryl scaffold for bioactivity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the bromine atom allows for further functionalization.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and other advanced functional materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems and mechanisms.

Basic Information

Product Name	1-Bromo-4-Cyclobutyl-Benzene
CAS No.	39868-71-8
Molecular Formula	C10H11Br
Molecular Weight	211.10 g/mol
Synonyms	4-Bromophenylcyclobutane; p-Bromophenylcyclobutane; 4-Cyclobutylbromobenzene; 1-Bromo-4-cyclobutylbenzene; (4-Bromophenyl)cyclobutane; Cyclobutylbenzene, 4'-bromo-; Benzene, 1-bromo-4-cyclobutyl-
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Cyclobutyl-Benzene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.