Description

2-Thiazolecarbonylchloride,5-Nitro-(9Ci) is a specialized heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists working on novel active ingredients, where its reactive carbonyl chloride and nitro-substituted thiazole core enable precise molecular modifications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or possessing specific biological activity profiles.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, leveraging the bioactive thiazole scaffold.
• Chemical Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and functional materials.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized dyes and pigments due to the nitro and heterocyclic components.

Basic Information

Product Name	2-Thiazolecarbonylchloride,5-Nitro-(9Ci)
CAS No.	39849-85-9
Molecular Formula	C4H1ClN2O3S
Molecular Weight	192.57 g/mol
Synonyms	5-Nitro-2-thiazolecarbonyl chloride; 5-Nitrothiazole-2-carbonyl chloride; 2-Thiazolecarbonyl chloride, 5-nitro-; 5-Nitro-1,3-thiazole-2-carbonyl chloride; 5-Nitrothiazole-2-carboxylic acid chloride; 5-Nitro-2-thiophenecarbonyl chloride (common misnomer); 5-Nitro-thiazole-2-carbonylchloride
EINECS	Contact for details

Quality Control

Our 2-Thiazolecarbonylchloride,5-Nitro-(9Ci) is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.