Description

4-[3-[(1,1-Dimethylethyl)Amino]-2-Hydroxypropoxy]-1H-Indole-2-Carboxylic Acid, 1-Methylethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex molecular structure. This compound is critical for the synthesis of specific active pharmaceutical ingredients (APIs) targeting complex biological pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for research into new therapeutic agents.
• Organic Synthesis Research: Used as a versatile intermediate in academic and industrial laboratories for constructing complex indole-based molecular architectures.
• Biochemical Research: Employed in the study of biological processes and the development of biochemical probes due to its specific functional groups.
• Process Development & Scale-up: Serves as a critical material for process chemistry teams optimizing synthetic routes from laboratory to commercial manufacturing scale.

Basic Information

Product Name	4-[3-[(1,1-Dimethylethyl)Amino]-2-Hydroxypropoxy]-1H-Indole-2-Carboxylic Acid, 1-Methylethyl Ester
CAS No.	39731-05-0
Molecular Formula	C19H28N2O5
Molecular Weight	364.44 g/mol
Synonyms	4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid isopropyl ester; Isopropyl 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylate; 1-Methylethyl 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1H-indole-2-carboxylate; Tert-butylamino-hydroxypropoxy indole carboxylate isopropyl ester; 39731-05-0; 4-(3-(tert-Butylamino)-2-hydroxypropoxy)-1H-indole-2-carboxylic acid 1-methylethyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.