Description

(R)-(-)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate CAS NO 39648-67-4 is a high-purity chiral phosphoric acid derivative, widely recognized as a powerful organocatalyst. This compound matters for its exceptional ability to induce enantioselectivity in a broad range of synthetic transformations, enabling the production of single-enantiomer molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in asymmetric synthesis.

Application

• Asymmetric Organocatalysis: A key catalyst for enantioselective Friedel-Crafts alkylations, Mannich reactions, and transfer hydrogenations.
• Pharmaceutical Intermediate Synthesis: Critical for constructing chiral active pharmaceutical ingredients (APIs) with high optical purity.
• Agrochemical Development: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Chiral Ligand & Auxiliary Precursor: Serves as a starting material for synthesizing more complex chiral ligands for metal catalysis.
• Material Science Research: Investigated for the development of chiral polymers and advanced functional materials.
• Academic & Process R&D: A fundamental tool for methodological development in academic laboratories and industrial process research.

Basic Information

Item	Details
Product Name	(R)-(-)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	39648-67-4
Molecular Formula	C₂₀H₁₃O₄P
Molecular Weight	348.29 g/mol
Synonyms	(R)-1,1'-Bi-2-naphthol Hydrogen Phosphate; (R)-BINOL Phosphoric Acid; (R)-3,3'-Bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diyl Hydrogenphosphate (precursor derivative); (R)-VAPOL Phosphoric Acid (related catalyst); (R)-TRIP; (R)-Phosphoric Acid Diester of BINOL; (R)-BINAP Acid; (R)-(-)-1,1'-Binaphthyl-2,2'-diyl Dihydrogen Phosphate
EINECS	Contact for details

Quality Control

Our (R)-(-)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification and purity assessment. Certificates of Analysis (COA) are provided, detailing specifications for identity, assay, and impurity profiles to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which may affect catalytic performance.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.