Description

2-Acetyl-5-Nitrothiophene is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the construction of complex molecular architectures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the nitro and acetyl functional groups for bioactivity.
• Material Science Research: Serves as a monomer or building block for creating conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized thiophene-based dyes and colorants.
• Academic & R&D: Employed in organic chemistry research for studying heterocyclic reactions, cyclization processes, and as a scaffold for combinatorial chemistry libraries.
• Chemical Synthesis: Utilized in various name reactions and as a starting material for further functionalization to create more complex thiophene derivatives.

Basic Information

Product Name	2-Acetyl-5-Nitrothiophene
CAS No.	39565-00-9
Molecular Formula	C6H5NO3S
Molecular Weight	171.17 g/mol
Synonyms	1-(5-Nitro-2-thienyl)ethanone; 5-Nitro-2-acetylthiophene; 2-Thienyl 5-nitro ketone; 2-Acetyl-5-nitro-thiophene; 5-Nitro-2-thienyl methyl ketone; Ethanone, 1-(5-nitro-2-thienyl)-; 5-Nitrothiophene-2-yl methyl ketone
EINECS	Contact for details

Quality Control

Every batch of 2-Acetyl-5-Nitrothiophene is manufactured and tested under strict quality management systems. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging. Separate from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.