Description

(R)-(-)-4-Phenyl-2-Butanol is a chiral secondary alcohol and a valuable enantiomerically pure building block in organic synthesis. Its defined stereochemistry is critical for producing compounds with specific biological activity, making it essential for research and development in high-value sectors. This intermediate is primarily sought after by the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and by fine chemical manufacturers for creating advanced flavors, fragrances, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Flavor and Fragrance Ingredient: Used in the production of high-value aromatic compounds and chiral flavorants where specific sensory profiles are required.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in catalytic asymmetric reactions to induce stereoselectivity.
• Liquid Crystal and Advanced Material Precursor: Employed in the research and development of chiral dopants for liquid crystal displays (LCDs) and other functional organic materials.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Academic and R&D Laboratories: A standard reagent for methodological studies in organic chemistry, catalysis, and stereochemistry research.

Basic Information

Product Name	(R)-(-)-4-Phenyl-2-Butanol
CAS No.	39516-03-5
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(R)-4-Phenylbutan-2-ol; (R)-(-)-4-Phenyl-2-butanol; (2R)-4-Phenyl-2-butanol; (R)-1-Methyl-3-phenylpropanol; (R)-4-Phenylbutan-2-ol; (R)-γ-Phenyl-β-methyl ethyl alcohol; (R)-Levodropropizine impurity; (R)-Form of 4-Phenyl-2-butanol
EINECS	Contact for details

Quality Control

Our (R)-(-)-4-Phenyl-2-Butanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]	-20° to -24° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.