Description

(-)-Pentazocine CAS NO 39188-58-4 is the levorotatory enantiomer of pentazocine, a synthetic opioid analgesic of the benzomorphan class. This high-purity chiral intermediate is critical for pharmaceutical research and development, particularly in the study of stereoselective receptor binding and activity. It is primarily utilized by advanced pharmaceutical manufacturers and research institutions engaged in the synthesis of novel analgesic agents, receptor studies, and the development of enantiomerically pure active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of advanced analgesic and opioid receptor modulator APIs.
• Analgesic Research: Used in preclinical and clinical research to investigate the pharmacology, efficacy, and side-effect profiles of stereospecific opioid compounds.
• Reference Standard: Serves as a high-purity chemical reference standard (CRS) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Neuropharmacology Studies: Employed in biochemical assays and receptor binding studies to understand the mechanism of action at κ-opioid and other related receptors.
• Process Development: Utilized in the development and optimization of asymmetric synthesis and chiral separation processes within fine chemical production.

Basic Information

Product Name	(-)-Pentazocine
CAS No.	39188-58-4
Molecular Formula	C19H27NO
Molecular Weight	285.43 g/mol
Synonyms	(-)-Pentazocine; Levopentazocine; (2R,6R,11R)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol; Win 20,228; 2'α,6α,11α-(–)-Pentazocine; Pentazocine, (-)-isomer; Pentazocine levo-isomer
EINECS	Contact for details

Quality Control

Our (-)-Pentazocine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, identity confirmation by IR and NMR, and stringent control of related substances. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0%
Related Substances (HPLC)	Total impurities ≤1.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.