Description

(E)-1-Bromo-3-Phenyl-2-Butene is a versatile brominated alkene intermediate with a defined stereochemistry. This compound is valued for its role as a key building block in organic synthesis, enabling the introduction of both a phenyl group and a reactive bromoalkene moiety. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring stereospecific carbon-carbon bond formation.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators where the phenyl-butene scaffold is a key structural component.
• Organic Synthesis Building Block: Serves as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Heck) and as a substrate for nucleophilic substitution reactions in academic and industrial R&D.
• Ligand and Material Science Precursor: Employed in the preparation of specialized ligands for catalysis or as a monomeric unit in the research of advanced polymeric materials.
• Flavor and Fragrance Industry: Acts as an intermediate for the synthesis of specific aromatic compounds used in high-value fragrance and flavor formulations.

Basic Information

Item	Details
Product Name	(E)-1-Bromo-3-Phenyl-2-Butene
CAS No.	39171-59-0
Molecular Formula	C10H11Br
Molecular Weight	211.10 g/mol
Synonyms	(E)-1-Bromo-3-phenylbut-2-ene; trans-1-Bromo-3-phenyl-2-butene; 1-Bromo-3-phenyl-2-butene (E)-; 3-Phenyl-2-buten-1-yl bromide; γ-Bromomethyl-β-methylstyrene; (E)-γ-Bromoisoeugenyl bromide; (E)-1-Bromo-3-phenylbut-2-ene
EINECS	Contact for details

Quality Control

Our (E)-1-Bromo-3-Phenyl-2-Butene is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Area %)
Isomeric Purity (E/Z ratio)	≥ 98:2 (by GC or HPLC)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.