Description

4-Amino-1,1-dioxo-tetrahydro-2H-thiopyran-4-carboxylic acid is a high-value, multifunctional heterocyclic building block containing both amino and carboxylic acid functional groups. This compound matters for its role as a key synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced organic materials. Pharmaceutical R&D teams and fine chemical manufacturers need it for constructing complex molecular architectures, particularly in medicinal chemistry programs targeting new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors due to its structural similarity to transition-state analogs.
• Peptidomimetic Synthesis: Serves as a constrained, non-proteinogenic amino acid analog for creating stable peptide-like molecules.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Ligand Development: Utilized in organometallic chemistry for creating novel chelating ligands with specific binding properties.
• Advanced Material Synthesis: Acts as a monomer or precursor for functional polymers and specialty coatings with tailored properties.

Basic Information

Product Name	4-Amino-1,1-dioxo-tetrahydro-2H-thiopyran-4-carboxylic Acid
CAS No.	39124-27-1
Molecular Formula	C6H9NO4S
Molecular Weight	191.21 g/mol
Synonyms	4-Amino-4-carboxy-tetrahydro-2H-thiopyran-1,1-dioxide; 4-Aminotetrahydro-2H-thiopyran-4-carboxylic acid 1,1-dioxide; 4-Amino-1,1-dioxo-1λ⁶-thiane-4-carboxylic acid; 4-Amino-1,1-dioxo-perhydro-2H-thiopyran-4-carboxylic acid; 4-Amino-tetrahydro-thiopyran-4-carboxylic acid S,S-dioxide; 4-Amino-4-carboxy-thiane 1,1-dioxide; 4-Amino-1,1-dioxo-thiane-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Amino-1,1-dioxo-tetrahydro-2H-thiopyran-4-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.