Description

Ethylenediamine-1,2-14C Dihydrochloride is a carbon-14 radiolabeled derivative of ethylenediamine dihydrochloride, serving as a critical tracer molecule in advanced research and development. Its primary value lies in enabling precise metabolic pathway studies, pharmacokinetic profiling, and environmental fate tracking through sensitive detection methods. This compound is essential for researchers and scientists in the pharmaceutical, agrochemical, and environmental science sectors who require high-purity isotopic labels for autoradiography, liquid scintillation counting, and mass spectrometry applications.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a radiolabeled precursor or intermediate to trace the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities in preclinical research.
• Agrochemical Research: Employed in environmental fate studies to track the degradation pathways, metabolite identification, and soil binding of herbicides, pesticides, or plant growth regulators.
• Biochemical Pathway Analysis: Facilitates the investigation of specific biochemical reactions and enzymatic processes where the ethylenediamine moiety is incorporated.
• Protein and Polymer Modification Studies: Acts as a tagged cross-linking or modifying agent to study biomolecular interactions or polymer functionalization.
• Analytical Method Development: Serves as a standard or reference material in developing and validating sensitive analytical methods like LC-MS/MS for detection of related compounds.

Basic Information

Product Name	Ethylenediamine-1,2-14C Dihydrochloride
CAS No.	39085-48-8
Molecular Formula	C214C2H10Cl2N2 *or* C2H8N2·2HCl (where two carbons are 14C)
Molecular Weight	~137.0 g/mol (for unlabeled form: 133.02 g/mol)
Synonyms	1,2-Ethylenediamine-14C Dihydrochloride; Ethane-1,2-diamine-1,2-14C Dihydrochloride; [1,2-14C]Ethylenediamine Dihydrochloride; 1,2-Diaminoethane-1,2-14C Dihydrochloride; EDA-1,2-14C·2HCl; Radiolabeled Ethylenediamine 2HCl; NSC 135799 (related); UNII identifier available upon request.
EINECS	Contact for details

Quality Control

Every batch of Ethylenediamine-1,2-14C Dihydrochloride is manufactured and controlled under strict quality systems to ensure identity, purity, and specific activity. We provide comprehensive Certificates of Analysis (COA) that detail critical parameters including radiochemical purity, chemical purity, specific activity (mCi/mmol or GBq/mmol), and solvent content. Our quality commitment aligns with the stringent requirements for radiolabeled compounds used in GLP (Good Laboratory Practice) and research settings.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere if specified and opened in a controlled, dry environment to maintain stability and specific activity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR/NMR)	Conforms to structure
Assay (HPLC/Titration)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (1.85-2.22 GBq/mmol) *or* Custom
Solvent Content (Residue on Evaporation)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.