Description

(2E)-3-Phenyl-1-(Thiophen-2-Yl)Prop-2-En-1-One CAS NO 39078-33-6 is a high-purity chalcone derivative, a versatile organic building block characterized by its phenyl and thiophene moieties. This compound is critical for advanced organic synthesis, offering a reliable scaffold for developing novel materials and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for applications in drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting anti-inflammatory, anticancer, or antimicrobial pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of advanced polymers and organic electronic materials.
• Chemical Synthesis: A versatile building block for creating complex heterocyclic compounds and chalcone analogs in medicinal chemistry.
• Academic & R&D: Employed in university and corporate research laboratories for studying structure-activity relationships (SAR) and reaction mechanisms.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	(2E)-3-Phenyl-1-(Thiophen-2-Yl)Prop-2-En-1-One
CAS No.	39078-33-6
Molecular Formula	C13H10OS
Molecular Weight	214.28 g/mol
Synonyms	2-Propen-1-one, 3-phenyl-1-(2-thienyl)-, (2E)-; (E)-3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one; 1-(2-Thienyl)-3-phenyl-2-propen-1-one; 2'-Thienylchalcone; 3-Phenyl-1-(2-thienyl)-2-propen-1-one; Thiophene-2-yl chalcone; (E)-1-(Thiophen-2-yl)-3-phenylprop-2-en-1-one
EINECS	Contact for details

Quality Control

Our (2E)-3-Phenyl-1-(Thiophen-2-Yl)Prop-2-En-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	98 - 102 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.