Description

6,7-Dimethoxy-1-(4-Methoxyphenyl)-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, synthetic organic compound belonging to the tetrahydroisoquinoline class, a structure of significant interest in medicinal chemistry. Its value lies in its role as a versatile and critical pharmaceutical intermediate for the research and development of novel therapeutic agents. This compound is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing complex molecules for preclinical and clinical studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting the central nervous system (CNS).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new analogs with optimized biological activity.
• Preclinical Drug Development: Serves as a precursor for compounds being evaluated in pharmacological and toxicological assays.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical products.
• Chemical Synthesis: Utilized in academic and industrial research for constructing complex heterocyclic frameworks.
• Biochemical Tool Compound: Potential use in probing biological pathways and enzyme interactions related to its structural class.

Basic Information

Product Name	6,7-Dimethoxy-1-(4-Methoxyphenyl)-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	38925-49-4
Molecular Formula	C19H23NO3·HCl
Molecular Weight	349.85 g/mol (Free base: 313.39 g/mol)
Synonyms	1-(4-Methoxyphenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 6,7-Dimethoxy-1-(4-methoxyphenyl)-3,4-dihydroisoquinoline hydrochloride; 1-(p-Methoxyphenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline HCl; NSC 113928; Tetrahydroisoquinoline derivative, 6,7-dimethoxy-1-(4-methoxyphenyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-1-(4-Methoxyphenyl)-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for materials intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.