Description

17β-Hydroxy-10-Methoxy-19α-Methyl-18-Oxayohimban-16α-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex natural products and the exploration of new bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct the core yohimbane or related indole alkaloid frameworks.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop analogs with modified biological activity and improved pharmacokinetic profiles.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Used as a tool compound to study interactions with biological targets such as specific receptors or enzymes.

Basic Information

Product Name	17β-Hydroxy-10-Methoxy-19α-Methyl-18-Oxayohimban-16α-Carboxylic Acid Methyl Ester
CAS No.	38839-94-0
Molecular Formula	C22H26N2O5
Molecular Weight	398.45 g/mol
Synonyms	Methyl 17β-hydroxy-10-methoxy-19α-methyl-18-oxayohimban-16α-carboxylate; 10-Methoxy-19α-methyl-18-oxayohimban-16α-carboxylic acid, 17β-hydroxy-, methyl ester; 18-Oxayohimban-16α-carboxylic acid derivative; Yohimbane alkaloid intermediate; Ajmalicine related intermediate; Tetrahydroalstonine analog
EINECS	Contact for details

Quality Control

Our 17β-Hydroxy-10-Methoxy-19α-Methyl-18-Oxayohimban-16α-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.