Description

Lithium Triisobutylhydroborate is a highly reactive organoboron compound used as a powerful and selective reducing agent in organic synthesis. Its value lies in its ability to perform stereoselective reductions of carbonyl groups and other functional groups under mild conditions, offering chemists precise control over reaction outcomes. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where high-purity intermediates are critical.

Application

• Stereoselective Carbonyl Reduction: For the precise synthesis of chiral alcohols, a key step in pharmaceutical active ingredient (API) manufacturing.
• Asymmetric Synthesis: As a reagent in the production of enantiomerically pure compounds for drug development and fine chemicals.
• Functional Group Transformation: Selective reduction of ketones, aldehydes, and imines in complex molecular structures.
• Hydroboration Agent: Used in hydroboration-oxidation reactions to convert alkenes to alcohols with anti-Markovnikov selectivity.
• Polymer Chemistry: As an initiator or modifying agent in the synthesis of specialty polymers and advanced materials.
• Academic & Industrial R&D: A valuable tool for methodological development and exploratory synthesis in research laboratories.

Basic Information

Product Name	Lithium Triisobutylhydroborate
CAS No.	38721-52-7
Molecular Formula	C12H28BLi
Molecular Weight	190.10 g/mol
Synonyms	Lithium Triisobutylborohydride; L-Selectride® (Trade Name); Lithium Tri-sec-butylborohydride; Lithium Hydrotriisobutylborate; Triisobutylborohydride Lithium Salt; Lithium Tris(2-methylpropyl)borohydride; (i-Bu)3BH Li+; LTBB
EINECS	Contact for details

Quality Control

Our Lithium Triisobutylhydroborate is manufactured under stringent controls to ensure high chemical purity and batch-to-batch consistency, suitable for demanding synthetic applications. Quality is verified through comprehensive analytical methods including NMR, titration, and Karl Fischer moisture analysis. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place. Due to its sensitivity to moisture and air, containers must be kept tightly sealed and handled under inert conditions to maintain purity and reactivity. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (Titration)	≥ 1.0 M in THF or specified solvent
Purity (NMR)	≥ 95%
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.