Description

1,3-Propane-2,2-D2-Diol is a deuterated derivative of 1,3-propanediol, where two hydrogen atoms are replaced by deuterium at the central carbon, making it a valuable isotopically labeled compound. This deuteration is critical for applications requiring enhanced stability, precise metabolic tracing, or altered spectroscopic properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for use as a building block in synthesis, a solvent in specialized reactions, and a probe in analytical and mechanistic studies.

Application

• Pharmaceutical Research & Development: As a deuterated building block for synthesizing Active Pharmaceutical Ingredients (APIs) with improved metabolic stability and pharmacokinetic profiles.
• Analytical Chemistry & Spectroscopy: Serving as an internal standard or probe in Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) for quantitative analysis and metabolic pathway studies.
• Organic Synthesis & Catalysis: Employed as a specialized solvent or reagent in deuterium-labeling reactions and mechanistic investigations to study reaction pathways.
• Agrochemical Development: Used in the synthesis of deuterated agrochemicals to potentially enhance environmental persistence and efficacy.
• Polymer Science: As a monomer or chain modifier in the production of specialized polymers, such as polyesters and polyurethanes, for research into material properties.
• Academic & Industrial Research: A key material for fundamental research in chemistry, biochemistry, and materials science involving isotope effects.

Basic Information

Product Name	1,3-Propane-2,2-D2-Diol
CAS No.	38645-14-6
Molecular Formula	C3H6D2O2
Molecular Weight	78.11 g/mol (approx.)
Synonyms	1,3-Propanediol-2,2-d2; [2,2-2H2]-1,3-Propanediol; 2,2-Dideutero-1,3-propanediol; Deuterated 1,3-Propanediol; 1,3-PDO-d2; Propane-1,3-diol-2,2-d2; 2,2-Dideuteriopropane-1,3-diol
EINECS	Contact for details

Quality Control

Our 1,3-Propane-2,2-D2-Diol is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR for isotopic purity and HPLC/GC for chemical purity and impurity profiling, to ensure it meets the high standards required for research and industrial use. A Certificate of Analysis (COA) detailing specific results for deuterium enrichment, chemical purity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.