Description

1-tert-Butyl-3-(Chloromethyl)Benzene is a versatile aromatic intermediate featuring both a tert-butyl group and a reactive chloromethyl substituent. This molecular structure makes it a valuable building block for the synthesis of more complex organic compounds, particularly in fine chemical and pharmaceutical manufacturing. It is primarily utilized by research and development chemists and production-scale operators in the agrochemical, pharmaceutical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a bulky, lipophilic tert-butyl aromatic moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where its structure can contribute to biological activity and stability.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in metal-catalyzed reactions and organometallic chemistry.
• Polymer Modification: Employed to introduce functional groups into polymer chains, modifying properties like solubility, thermal stability, or reactivity.
• Organic Synthesis Building Block: The reactive chloromethyl group allows for further functionalization through nucleophilic substitution, making it useful for constructing complex molecular architectures in research.
• Material Science Research: Investigated for the preparation of novel organic frameworks and advanced materials with specific electronic or structural properties.

Basic Information

Item	Details
Product Name	1-tert-Butyl-3-(Chloromethyl)Benzene
CAS No.	38580-79-9
Molecular Formula	C11H15Cl
Molecular Weight	182.69 g/mol
Synonyms	3-(Chloromethyl)-1-tert-butylbenzene; 1-tert-Butyl-3-(chloromethyl)benzene; 3-(tert-Butyl)benzyl chloride; m-tert-Butylbenzyl chloride; (3-tert-Butylphenyl)methyl chloride; 38580-79-9; Benzene, 1-(1,1-dimethylethyl)-3-(chloromethyl)-; 3-tert-Butylbenzyl chloride
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-3-(Chloromethyl)Benzene is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including assay (HPLC), identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to exclude moisture. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.