Description

Iodocyclobutane is a valuable halogenated organic building block, specifically a four-membered cyclic alkyl iodide. Its primary commercial value lies in its utility as a versatile intermediate in advanced organic synthesis, particularly for constructing strained ring systems and introducing functional groups via nucleophilic substitution or cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing cyclobutane rings, which are of increasing interest in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides that incorporate halogenated cyclic structures.
• Cross-Coupling Reactions: Serves as an electrophilic coupling partner in metal-catalyzed reactions (e.g., Negishi, Stille, Suzuki-Miyaura) to form carbon-carbon bonds.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Polymer & Material Science: Acts as a monomer or functionalization agent in the production of specialty polymers and advanced materials with unique properties.
• Organic Synthesis Research: A fundamental reagent in academic and industrial R&D for exploring new reaction methodologies and constructing complex molecular architectures.

Basic Information

Product Name	Iodocyclobutane
CAS No.	38557-29-8
Molecular Formula	C4H7I
Molecular Weight	182.00 g/mol
Synonyms	Cyclobutyl iodide; Cyclobutane, iodo-; Iodocyclobutane; 1-Iodocyclobutane; Cyclobutyl iodide (6CI,7CI,8CI); NSC 60548
EINECS	Contact for details

Quality Control

Our Iodocyclobutane is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in opaque secondary packaging.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.