Description

(20β)-17-Hydroxycorynan-5β,16-Dicarboxylic Acid 16-Methyl Ester is a high-purity, complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate for the development of novel therapeutic agents and for studying complex biochemical pathways. It is primarily sought by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of specialized alkaloid-based compounds.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting neurological or other specialized receptors.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate enzyme interactions and receptor binding mechanisms related to indole alkaloids.
• Organic Synthesis: Serves as a sophisticated starting material or intermediate for the total synthesis of complex natural products and for method development in stereoselective chemistry.
• Academic Research: Employed in university and institutional laboratories for fundamental studies in medicinal chemistry and natural product synthesis.
• Fine Chemical Production: Utilized in the manufacture of high-value, low-volume specialty chemicals for research and diagnostic markets.

Basic Information

Item	Detail
Product Name	(20β)-17-Hydroxycorynan-5β,16-Dicarboxylic Acid 16-Methyl Ester
CAS No.	38474-14-5
Molecular Formula	C22H26N2O5
Molecular Weight	398.45 g/mol
Synonyms	16-Methyl (20β)-17-hydroxycorynan-5β,16-dicarboxylate; Methyl 17-hydroxycorynan-16-carboxylate derivative; Corynan-16-carboxylic acid, 17-hydroxy-, methyl ester, (5β,20β)-; Alkaloid Yohimbine derivative intermediate; 38474-14-5; 17-Hydroxycorynan-16-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of (20β)-17-Hydroxycorynan-5β,16-Dicarboxylic Acid 16-Methyl Ester is produced and tested under a strict quality management system to ensure identity, purity, and consistency. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC, NMR, and mass spectrometry data. Our quality protocols are designed to meet the exacting standards required for pharmaceutical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.