Description

α-n-Normethadol is a synthetic opioid compound with a distinct chemical structure related to methadone. This specialized intermediate is of significant value in pharmaceutical research and development, particularly for studying analgesic pathways and receptor interactions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and analytical laboratories focusing on neuropharmacology and controlled substance analysis.

Application

• Pharmaceutical Research Intermediate: Serves as a key synthetic precursor or reference standard in the development and study of opioid analgesics.
• Analytical Reference Standard: Used in qualitative and quantitative analysis (e.g., HPLC, GC-MS) for method development, validation, and forensic testing.
• Biochemical Research: Employed in in-vitro studies to investigate ligand-receptor binding kinetics and pharmacological profiles at opioid receptors.
• Metabolite Studies: Acts as a reference compound for the identification and characterization of metabolic pathways and related substances.
• Controlled Substance Analysis: Provides a critical standard for forensic and regulatory laboratories involved in drug identification and purity assessment.

Basic Information

Product Name	α-n-Normethadol
CAS No.	38455-85-5
Molecular Formula	C₂₁H₂₇NO
Molecular Weight	309.45 g/mol
Synonyms	α-n-Normethadol; 6-(Dimethylamino)-4,4-diphenyl-3-heptanol; Nor-α-methadol; α-Normethadol; DL-α-Normethadol; (±)-α-Normethadol; NSC 112597
EINECS	Contact for details

Quality Control

Our α-n-Normethadol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and identity confirmation. Certificates of Analysis (COA) detailing purity, chromatographic data, and other critical parameters are available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.