Description

1-Bromoazetidine is a versatile and highly reactive heterocyclic building block, essential for advanced organic synthesis. Its value lies in the azetidine ring, a strained four-membered nitrogen heterocycle, which imparts unique conformational and pharmacological properties when incorporated into target molecules. This compound is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for constructing azetidine-containing drug candidates, including protease inhibitors, kinase inhibitors, and other bioactive molecules targeting the central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the azetidine moiety can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of polymers and functional materials with specific thermal or electronic properties derived from the incorporated heterocycle.
• Chemical Biology Probes: Utilized to introduce the azetidine scaffold into molecules designed to study biological pathways and protein functions.

Basic Information

Product Name	1-Bromoazetidine
CAS No.	38455-26-4
Molecular Formula	C3H6BrN
Molecular Weight	135.99 g/mol
Synonyms	Azetidine, 1-bromo-; 1-Bromo-azetidine; Azetidin-1-yl bromide; 1-Bromoazacyclobutane; Bromoazetidine; N-Bromoazetidine; Azetidine hydrobromide (salt form); 38455-26-4
EINECS	Contact for details

Quality Control

Our 1-Bromoazetidine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Due to its light-sensitive nature and reactivity, it is recommended to handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.