Description

1-Naphthaleneethanol,Decahydro-2-Hydroxy- 2,5,5,8A-Tetramethyl-,(1R,2R,4As,8As)- is a high-purity, stereochemically defined decalin derivative with significant utility in advanced organic synthesis. This compound matters as a versatile chiral building block and intermediate, enabling the construction of complex molecular architectures with precise stereocontrol. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fragrance sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug candidates, particularly those with steroid-like or terpenoid frameworks.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the rigid decalin structure and specific stereochemistry can influence biological activity.
• Fragrance & Flavor Chemistry: Acts as a precursor for synthetic musks, amber notes, and other high-value aroma chemicals due to its polycyclic, terpenoid-like structure.
• Material Science Research: Investigated as a monomer or additive for specialty polymers and liquid crystals, leveraging its rigid, hydrophobic backbone.
• Catalyst & Ligand Development: Employed in the design and synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & Process Chemistry: Utilized in methodological studies and scale-up processes for stereoselective synthesis and natural product total synthesis.

Basic Information

Product Name	1-Naphthaleneethanol,Decahydro-2-Hydroxy- 2,5,5,8A-Tetramethyl-,(1R,2R,4As,8As)-
CAS No.	38419-75-9
Molecular Formula	C₁₆H₂₈O₂
Molecular Weight	252.39 g/mol
Synonyms	(1R,2R,4aS,8aS)-Decahydro-2-hydroxy-2,5,5,8a-tetramethyl-1-naphthaleneethanol; (1R,2R,4aS,8aS)-1-(2-Hydroxyethyl)decahydro-2,5,5,8a-tetramethyl-2-naphthol; 2-[(1R,2R,4aS,8aS)-Decahydro-2-hydroxy-2,5,5,8a-tetramethyl-1-naphthyl]ethanol; A Tetramethyl Decalin Ethanol Derivative; Chiral Decalin Diol Derivative; Polycyclic Terpenoid Intermediate
EINECS	Contact for details

Quality Control

Our 1-Naphthaleneethanol,Decahydro-2-Hydroxy- 2,5,5,8A-Tetramethyl-,(1R,2R,4As,8As)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research and development grade specifications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment to guarantee traceability and consistency for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.