Description

1'H-5α-Cholest-2-Eno[3,2-B]Indol-6-One is a high-purity, complex steroidal indole derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical advanced intermediate or reference standard for the development of novel bioactive molecules. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in steroid chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel steroidal drugs and investigational new chemical entities (NCEs).
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies targeting hormone receptors or other biological pathways.
• Biochemical Research: Employed in studies investigating the interaction of modified steroid structures with enzymes or cellular receptors.
• Organic Synthesis: Acts as a sophisticated starting material for the preparation of more complex, functionalized steroidal indole derivatives.

Basic Information

Item	Details
Product Name	1'H-5α-Cholest-2-Eno[3,2-B]Indol-6-One
CAS No.	38389-28-5
Molecular Formula	C₃₃H₄₅NO
Molecular Weight	471.72 g/mol
Synonyms	1'H-5α-Cholest-2-eno[3,2-b]indol-6-one; 5α-Cholest-2-eno[3,2-b]indol-6(1'H)-one; Steroidal[3,2-b]indole derivative; Cholestenoindolone; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1'H-5α-Cholest-2-Eno[3,2-B]Indol-6-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurities is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound should be handled and stored in accordance with good laboratory practices for sensitive organic intermediates.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.