Description

4-Oxotetrahydrothiophene-2,3-Dicarboxylic Acid Dimethyl Ester is a high-purity, versatile sulfur-containing heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both a thiophene-derived lactam and diester functionalities, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of functional polymers and advanced organic materials with specific electronic or structural properties.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	4-Oxotetrahydrothiophene-2,3-Dicarboxylic Acid Dimethyl Ester
CAS No.	38293-63-9
Molecular Formula	C9H12O5S
Molecular Weight	232.25 g/mol
Synonyms	Dimethyl 4-oxotetrahydrothiophene-2,3-dicarboxylate; 2,3-Dicarbomethoxy-4-oxotetrahydrothiophene; 4-Oxo-2,3-tetrahydrothiophenedicarboxylic Acid Dimethyl Ester; 4-Oxothiolane-2,3-dicarboxylic Acid Dimethyl Ester; 2,3-Bis(methoxycarbonyl)-4-oxotetrahydrothiophene; Thiophene-2,3-dicarboxylic acid, tetrahydro-4-oxo-, dimethyl ester; 38293-63-9; Dimethyl 4-oxotetrahydrothiophene-2,3-dicarboxylate
EINECS	Contact for details

Quality Control

Our 4-Oxotetrahydrothiophene-2,3-Dicarboxylic Acid Dimethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.