Description

1,4-Butanediol-2,2,3,3-D4 is a deuterium-labeled analog of 1,4-butanediol, a valuable chemical building block. This isotopically enriched compound is essential for advanced research and development, particularly in analytical chemistry and metabolic studies, where it serves as a stable internal standard. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications requiring precise molecular tracing and quantification.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in GC-MS and LC-MS analyses to ensure accuracy in the measurement of 1,4-butanediol and related metabolites.
• Metabolic Pathway Tracing: Employed in pharmacokinetic and drug metabolism studies to track the absorption, distribution, metabolism, and excretion (ADME) of compounds.
• NMR Spectroscopy Solvent & Reagent: Acts as a deuterated solvent or reagent in nuclear magnetic resonance (NMR) spectroscopy to eliminate interfering proton signals.
• Pharmaceutical Research: Facilitates the development and quality control of active pharmaceutical ingredients (APIs) and finished drug products through precise analytical methods.
• Polymer Science Research: Used in the synthesis and study of deuterated polymers to investigate polymer dynamics, structure, and properties.
• Forensic and Clinical Toxicology: Aids in the accurate identification and quantification of substances in complex biological matrices.

Basic Information

Product Name	1,4-Butanediol-2,2,3,3-D4
CAS No.	38274-25-8
Molecular Formula	C4D4H4O2
Molecular Weight	94.12 g/mol
Synonyms	1,4-Butanediol-d4; Butane-1,4-diol-2,2,3,3-d4; Tetradeutero-1,4-butanediol; [2,2,3,3-2H4]-1,4-Butanediol; BDO-d4; 1,4-BD-d4; Deuterated 1,4-Butanediol; 1,4-Butylene Glycol-d4
EINECS	Contact for details

Quality Control

Our 1,4-Butanediol-2,2,3,3-D4 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) detailing assay, isotopic enrichment, and impurity profiles to meet the exacting standards of research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.