Description

3,14-Dimethoxy-17-Methyl-4,5α-Epoxymorphinan-6-One is a high-purity synthetic opioid alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of specialized analgesics and other therapeutic agents, where precise chemical structure and purity are paramount. It is essential for research institutions, pharmaceutical companies, and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs) and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent opioid analgesics and related medicinal compounds.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control testing of pharmaceutical products.
• Biochemical Research: Employed in preclinical studies to investigate opioid receptor binding, pharmacology, and metabolic pathways.
• Process Chemistry: Serves as a starting material or intermediate in process development and scale-up for API manufacturing under controlled GMP environments.
• Forensic Analysis: Utilized as an analytical standard for the identification and quantification of substances in forensic toxicology.

Basic Information

Product Name	3,14-Dimethoxy-17-Methyl-4,5α-Epoxymorphinan-6-One
CAS No.	38252-28-7
Molecular Formula	C20H25NO4
Molecular Weight	343.42 g/mol
Synonyms	3,14-Dimethoxy-17-methyl-4,5α-epoxymorphinan-6-one; 6-Oxo-3,14-dimethoxy-17-methyl-4,5α-epoxymorphinan; 4,5α-Epoxy-3,14-dimethoxy-17-methylmorphinan-6-one; Oripavine derivative; Thebaine derivative; Opioid alkaloid intermediate
EINECS	Contact for details

Quality Control

Our production of 3,14-Dimethoxy-17-Methyl-4,5α-Epoxymorphinan-6-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and handled in a controlled environment suitable for advanced intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.