Description

5-Methyl-3,4-Dihydro-2H-Pyrrole-2-Carboxylic Acid Hydrochloride is a high-purity organic salt derivative of a dihydropyrrole carboxylic acid, serving as a critical building block and intermediate in advanced chemical synthesis. Its value lies in providing a functionalized, protected scaffold essential for constructing complex nitrogen-containing heterocycles. This compound is primarily needed by pharmaceutical research and fine chemical manufacturers developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Building block for developing new generation pesticides and herbicides with specific biological activity.
• Peptidomimetics & Prodrug Design: Used to incorporate the dihydropyrrole moiety into peptide backbones or as a pro-moiety to modify drug properties like solubility and bioavailability.
• Chemical Biology Probes: Serves as a scaffold for creating tool compounds and probes to study enzyme function and biological pathways.
• Material Science: Intermediate in the production of specialty polymers and functional materials requiring specific nitrogen heterocycles.
• Academic & Contract Research: Essential reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	5-Methyl-3,4-Dihydro-2H-Pyrrole-2-Carboxylic Acid Hydrochloride
CAS No.	38228-01-2
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	2H-Pyrrole-2-carboxylic acid, 3,4-dihydro-5-methyl-, hydrochloride (1:1); 5-Methyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid hydrochloride; 5-Methyl-δ3-pyrroline-2-carboxylic acid hydrochloride; 2-Carboxy-5-methyl-3-pyrroline hydrochloride; 5-Methyl-1,2,3,6-tetrahydropyridine-2-carboxylic acid hydrochloride (tautomeric form); 5-Methyl-3,4-dihydro-2H-pyrrole-2-carboxylic acid HCl
EINECS	Contact for details

Quality Control

Our 5-Methyl-3,4-Dihydro-2H-Pyrrole-2-Carboxylic Acid Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.